Welcome to the Mentzer Lab

A focus of our laboratory is the adaptive and regenerative processes contributing to tissue repair and regeneration. These processes typically involve blood vessel growth (angiogenesis) and changes in the organ surface (mesothelial-mesenchymal transition). The study of these processes involves a multi-scale approach: 1) the regulated expression of genes and molecules, 2) the interactive signaling communication between cells, and 3) the structural/biomechanical relationships leading to adult tissue remodeling (morphogenesis). A recent focus of our approach has been the use of biologic polymers(such as pectin) as tools to explore mesothelial-mesenchymal transition and other fundamental processes essential to normal tissue repair and regeneration. The perturbation of these processes is a major contributor to lung disease and lung cancer.

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news

We are accepting applications for a funded Surgical Research Fellowship (US Citizens or equivalent currently in an American surgical residency) beginning in July 2025. Competitive Fellowships are also available starting July 2026. Contact us for details.
Congratulations to Max Ackermann as he has been awarded the prestigious Rudolf Virchow Prize by the the Deutsche Gesellshaft fur Pathologie..
Dr. Jennifer Pan presented "Mesothelial Cell Dynamics in Visceral Organs" at Harvard Research Day, October 1, 2024..
Anuhya Dayal presented "Facilitated Transport Across Glycocalyceal Barriers in the Chick Chorioallantoic Membrane" at the Academic Surgical Congress in Washington DC February 6, 2024. .
Dr. Betty Liu presented "Structural heteropolysaccharide adhesion to the corneal glycocalyx" at Experimental Biology in Philadelphia on April 5, 2022..
Matthew Liao presented "Kinetics of plant-derived heteropolysaccharide bioabsorption characterized by a fluorescence-based microfluidics system" at Experimental Biology in Philadelphia on April 5, 2022..